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HSC 310 - Evidence Based Health Care: Finding Research

Original Research Articles (requires a good search & critical appraisal of articles)

PICO Framework

Once you have developed your clinical question, use the PICO framework to develop keywords to search for relevant evidence. 





Population, Patient, Problem

Intervention or Exposure



What are the characteristics of the patient, population, or problem?

What is the condition or disease you are looking at?

What do you want to do for the patient or population?

Are there alternative treatments to compare with the intervention?

What do you expect to accomplish, improve, or affect?

What is a Literature Review

Literature Review:
A literature review gives an overview of the field of inquiry: what has already been said on the topic, who the key writers are, what the prevailing theories and hypotheses are, what questions are being asked, and what methodologies and methods are appropriate and useful.

Critically-appraised individual articles evaluate and synopsize individual research studies.

Systematic Review:
A systematic review is a type of literature review that attempts to identify, appraise and synthesize all the empirical evidence that meets pre-specified eligibility criteria to answer a given research question. Researchers conducting systematic reviews use explicit methods aimed at minimizing bias, in order to produce more reliable findings that can be used to inform decision making.


Search eBooks using the Library Searchbar and limit to eBooks, or use these eBook databases that have Health information specifically:

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